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The 4100s DE was a D'ni decade which began on Leefo 1 4100 DE, and ended on Leenovoo 29 4124 DE.
- King Ishek's wife is abducted by inhabitants of the Age of Yimas while she and her husband toured the Age's food facility. She is held captive by the natives, who demand Ages of their own to rule.
- The Relyimah rescue the king's wife and apprehend the kidnappers, believed to be members of either the Blood of Yahvo or Light of D'ni cults.